The notion of conceivability has traditionally been regarded as crucial to an account of modal knowledge. Despite its importance to modal epistemology, there is no received explication of conceivability. One purpose of this paper is to argue that the notion is not fruitfully explicated in terms of the imagination. The most natural way of presenting a notion of conceivability qua imaginability is open to cogent criticism. In order to avoid such criticism, an advocate of the modal insightfulness of the imagination (...) must broaden the idea of what it is to be imaginable. I argue that this required broadening renders the imagination idle . Consequently, I distinguish two different accounts of the evidential basis of modal knowledge and present a more general argument that concludes that the very notion of conceivability should be eschewed in modal epistemology. (shrink)

Contingency is the presence of non-actualized possibility in the world. Fatalism is a view of reality on which there is no contingency. Since it is contingency that permits agency, there has traditionally been much interest in contingency. This interest has long been embarrassed by the contention that simple and plausible assumptions about the world lead to fatalism. I begin with an Aristotelian argument as presented by Richard Taylor. Appreciation of this argument has been stultified by a question pertaining to the (...) source of necessity and possibility and a closely related one regarding the nature of metaphysics itself. Answering these questions reveals the crucial issue here, to wit, necessity and possibility in a temporal world. This issue is investigated through an important later criticism of Taylor by David Foster Wallace. Wallace’s critique is significant because it brings to the fore the pivotal notion for understanding contingency in a temporal world, that of synchronic possibility, the idea that incompatible states of affairs are possible at a single moment. This notion provides the basis of distinguishing two systematic accounts of truth, modality and time: two metaphysics of contingency. On one account, Taylor’s Aristotelian argument is straightforwardly valid and compelling; on the other, it is fallacious. In closing, I present reasons why the former account, supporting the Aristotelian views of time and truth, is correct and make some comments to ameliorate this conclusion. (shrink)

Each thing is fundamental. Not only is no thing any more or less real than any other, but no thing is prior to another in any robust ontological sense. Thus, no thing can explain the very existence of another, nor account for how another is what it is. I reach this surprising conclusion by undermining two important positions in contemporary metaphysics: hylomorphism and hierarchical views employing so-called building relations, such as grounding. The paper has three main parts. First, I observe (...) hylomorphism is alleged by its proponents to solve various philosophical problems. However, I demonstrate, in light of a compelling account of explanation, that these problems are actually demands to explain what cannot be but inexplicable. Second, I show how my argument against hylomorphism illuminates an account of the essence of a thing, thereby providing insight into what it is to exist. This indicates what a thing, in the most general sense, must be and a correlative account of the structure in reality. Third, I argue that this account of structure is incompatible not only with hylomorphism, but also with any hierarchical view of reality. Although hylomorphism and the latter views are quite different, representing distinct philosophical traditions, I maintain they share untenable accounts of structure and fundamentality and so should be rejected on the same grounds. (shrink)

A perennial epistemological question is whether things can be known just as they are in the absence of any awareness of them. This epistemological question is posterior to ontological considerations and more specific ones pertaining to mind. In light of such considerations, the author propounds a naïve realist, foundationalist account of knowledge of things in themselves, one that makes crucial use of the work of Brentano. After introducing the resources provided by Brentano’s study of mind, the author reveals the ontological (...) framework in which it takes place. Doing so is instrumental to illuminating acquaintance, the state that enables the direct engagement of a mind and some other thing. The author discusses this state and shows how it has the epistemic heft, with a Brentanian account of judgment, to provide the foundations of one’s knowledge of the world. A naïve realist, foundationalist account of knowledge is open to a compelling objection; the author presents this objection with the means of undermining it. In conclusion, the author recurs to the opening theme of the primacy of ontology and suggests that familiar misgivings about knowing things in themselves are all based on questionable—and ultimately untenable—ontological presuppositions. (shrink)

‘Thing’ in the titular question should be construed as having the utmost generality. In the relevant sense, a thing just is an entity, an existent, a being. The present task is to say what a thing of any category is. This task is, I believe, the primary one of any comprehensive and systematic metaphysics. Indeed, an answer provides the means for resolving perennial disputes concerning the integrity of the structure in reality—whether some of the relations among things are necessary merely (...) given those relata themselves—and the intricacy of this structure—whether some things are more or less fundamental than others. After considering some reasons for thinking the generality of the titular question makes it unanswerable, I propound the methodology, original inquiry, required to answer it. The key to this methodology is adopting a singular perspective; confronting the world as merely the impetus to inquiry, one can attain an account of what a thing must be. Radical ontology is a systematic metaphysics—broadly Aristotelian, essentialist and nonhierarchical—that develops the consequences of this account. With it, it is possible to move past stalemate in metaphysics by revealing the grounds of a principled choice between seemingly incommensurable worldviews. (shrink)

The purpose of this paper is to propose and defend an absolute principle of truthmaking, a maximalist one according to which every truth is made true by something in the world beyond itself. I maintain that an absolute principle must be true, that any weakened version is straightforwardly contradictory or incoherent. I criticize one principle of truthmaking (in terms of bald necessity) and articulate one in terms of the relation in virtue of. I then criticize other principles of truthmaking in (...) light of the latter, for I contend that in virtue of has a role in the theory of truthmaking that is essential and ineluctable. That all true representations have a truthmaker as defined by the principle I articulate is the absolute principle of truthmaking I defend. The crux of the paper is the arguments I present in defense of this absolute principle. In defending it against familiar objections to maximalism, an account of the truthmakers that seem to ground all true representations emerges. I maintain that such truthmakers are simple facts. With the absolute principle and its corollary account of truthmakers, this paper contains the core of a comprehensive theory of truthmaking. (shrink)

In this paper, I answer the question of what time is. First, however, I consider why one might ask this question and what exactly it is asking. The latter consideration reveals that in order to answer the question, one must first engage in a more basic investigation of what a thing, anything at all, is. Such radical investigation requires a special methodology. After briefly characterizing this methodology, I show how it can be employed to answer the titular question. This answer (...) is significant not merely because it illuminates something of perennial interest, but because it is essential to a comprehensive and fully satisfactory metaphysics of time and, hence, to a view of the full structure in reality. (shrink)

Presentism is a controversial and much discussed position in the metaphysics of time. The position is often glossed as simply the view that everything that exists is present. This gloss, however, does not in itself characterize a single view. In this paper, I first propound the variety of presentist views, characterizing the primary dimensions along which the views differ. I then present the version of presentism I deem optimal. The variety among presentist views is so great that the version that (...) I prefer and shall defend—transient presentism—is not even characterized by the standard gloss given above. I next discuss all of the objections to presentism of which I am aware, considering the relevance of each to transient presentism. I conclude that transient presentism provides the most satisfying responses to the traditional objections and, furthermore, captures very well the motivation for adopting a presentist position in the first place. The grounds for these two conclusions constitute my defense of transient presentism. (shrink)

Considering whether existence, i.e., being, is a thing might seem like the height of aimless metaphysical chin stroking. However, the issue—specifically, whether existence is a quality—is significant, bearing on how reality, this all-encompassing totality, is. On one view, reality at large is ontologically fixed, the sum total of things does not (and cannot) vary; on another view, reality is ontologically transient, the sum total of things varies. I first show that if existence is a thing, that reality is ontologically fixed (...) follows. So I consider whether existence is indeed a thing. I demonstrate that “it” could not be: existence is no existent. I then discuss what it is to exist, given existence is nothing at all. I maintain there are no grounds for the view that reality is ontologically fixed. I argue, from the irrefragable basis of temporal differentiation—the world going from thus…to as so—that reality is ontologically transient. I consider some objections to ontological transience and conclude by considering the key to understanding the overall structure in reality and what it reveals about how very inconstant all this is. (shrink)

There are two conspicuous and inescapable features of this world in which time is real. One experiences a world in flux, a transient world in which things constantly come into existence, change and cease to be. One also experiences a stable world, one in which how things are at any given moment is permanent, unchangeable. Thus, there is transience and permanence. Yet these two features of the world seem incompatible. The primary purpose of this paper is to sketch a metaphysics (...) of time that embraces both features. Crucial to this undertaking is the notion of becoming, that is, coming into existence. I distinguish three distinct phenomena of becoming: temporal, absolute and atemporal. The last is the least familiar of these; it is the phenomenon of coming into existence outside of time. Although the idea that there are things that do not exist in time is not unfamiliar, it is largely taken for granted that if anything comes into existence, it must do so in time. (Indeed, I suspect many think that the idea of a thing coming to be outside of time is simply incoherent.) In this paper, I articulate and defend the notion of atemporal becoming. It is by means of this notion that one can develop a fully satisfactory metaphysics of time, one that honors both transience and permanence and finds for each its proper domain within the world. (shrink)

The given is the state of a mind in its primary engagement with the world. A satisfactory epistemology—one, it turns out, that is foundationalist and includes a naïve realist view of perception—requires a certain account of the given. Moreover, knowledge based on the given requires both a particular view of the world itself and a heterodox account of judgment. These admittedly controversial claims are supported by basic ontological considerations. I begin, then, with two contradictory views of the world per se (...) and the structure one experiences. I draw out the consequences of these two views for what intentionality is. The two views yield incompatible accounts of the given. The definitive spontaneity of the one account, and passivity of the other, can be understood in terms of the structure (or lack thereof) in the given. In defense of the claim that a structured given is not an apt epistemic basis, I examine an attempt to found an epistemology on such an account in light of the so-called myth of the given. I maintain that the given, if it is to provide some justification for taking the world to be a particular way, must be unstructured. To support this, I first discuss a significant problem with traditional foundationalism. I then argue that a satisfactory (foundationalist) epistemology requires the rejection of the orthodox propositional view of judgment in favor of a non-propositional, reistic view. (shrink)

Some have concluded that the only appropriate response to the problem of temporary intrinsics is the view that familiar, concrete objects persist through time by perduring, that is, by having temporal parts. Many, including myself, believe this view of persistence is false, and so reject this conclusion. However, the most common attempts to resolve the problem and yet defend the view that familiar, concrete objects endure are self-defeating. This has heretofore gone unnoticed. I consider the most familiar such attempts, based (...) on a strategy called tensing the copula , and present a general argument to demonstrate why this strategy – and any strategy based on relativization – fails. I then show how the considerations raised in this general argument undermine other attempts to resolve the problem while denying perdurance. All these attempts are undermined by an assumption essential to the problem of temporary intrinsics, to wit, that there are many moments of time and all have the same ontological status. As long as this assumption is maintained, the only solution to the problem is that familiar, concrete objects perdure. Thus, in order to defend the view that objects persist through time by enduring, one must adopt a different metaphysics of time (viz., presentism). I conclude that it is neither unreasonable nor impracticable to do so. (shrink)

In this paper, I argue that how a mind can come to be about an object and how the world is independently of the workings of any mind are inextricably linked. Hence, epistemology, at its most basic, and metaphysics are systematically related. In order to demonstrate the primary thesis of the paper, I first articulate two contrary accounts of the nature of reality and then two contradictory general views of intentionality. I argue that these positions can be combined in only (...) two ways. This argument turns on the impossibility of there being an object that cannot, in principle, be thought of or referred to, so I present reasons for thinking such a thing cannot exist. The upshot is that there are but two intentional-cum-ontological positions, that is, two unified positions regarding how a mind relates to the world and what the world is like in itself. This might be surprising, for one might have thought that the views in the different domains were independent; it is significant, because it shows that views that might have seemed related by mere affinity are, in fact, necessarily conjoined. I conclude by presenting reasons for thinking one of the two intentional-cum-ontological positions is untenable. (shrink)

It is plausible that every true representation is made true by something in the world beyond itself. I believe that a simple fact is the truthmaker of each true proposition. Simple facts are not familiar entities. This lack of familiarity might lead many to regard them with suspicion, to think that including them in one’s ontology is an ad hoc maneuver. Although such suspicion is warranted initially, it is, I believe, ultimately unfounded. In this paper, I first present what I (...) take to be the simplest argument for simple facts. I then clarify what a simple fact is supposed to be by elucidating the way in which such entities are simple and elaborating an account of their nature. The simplest argument for simple facts relies on a premise that is deeply plausible and yet not uncontroversial, so I present a second argument that forgoes this premise. The second argument is more subtle—and shows the relevance to this discussion of unity from complexity, a metaphysical notion of profound importance—and yet leads to the same conclusion: simple facts exist. I end by considering some concerns one might have regarding the existence of simple facts or the fundamental role that I maintain they have in making true our thoughts and claims about the world. (shrink)

I first distinguish several notions that have traditionally been conflated (or otherwise neglected) in discussions of the metaphysics of time. Thus, for example, I distinguish between the passage of time and temporal becoming. The former is, I maintain, a confused notion that does not represent a feature of the world; whereas a proper understanding of the latter provides the key for a plausible and comprehensive account of the nature of temporal reality. There are two general classes of views of the (...) nature of temporal reality; proponents of particular views in both classes attempt to account for the phenomenon of temporal becoming in terms of qualitative change. I argue that any such account – in terms of change – is irredeemably problematic. And so I propound a different account of temporal becoming, based on the notion that temporal reality is transient, which provides the means to characterize intuitively and vividly the significant effects of time on the metaphysical nature of the world. (shrink)

Consequentialism is a general approach to understanding the nature of morality that seems to entail a certain view of the world in time. This entailment raises specific problems for the approach. The first seems to lead to the conclusion that every actual act is right – an unacceptable result for any moral theory. The second calls into question the idea that consequentialism is an approach to morality, for it leads to the conclusion that this approach produces a theory whose truth (...) does not depend in any way on the nature of rational beings or value. (shrink)

Several have denied that there is, specifically, a criterion of identity for persons and some deny that there are, for any kind, diachronic criteria of identity. I argue, however, that there are no criteria of identity, either synchronic or diachronic, for any kind whatsoever. I begin by elaborating the notion of a criterion of identity in order to clarify what exactly is being denied when I maintain there are none. I examine the motivation of those who qualify in some way (...) the general claim that there are synchronic and diachronic criteria of identity for every kind, then present my direct and categorical argument against such criteria. I next evaluate the objections of those who argue that rejecting criteria of identity has untenable results. These objections are ineffective, each based on the incorrect assumption that if there is no criterion of identity for a kind, the identity of an instance of that kind is independent of its qualities. I conclude by considering some of the upshots of rejecting criteria of identity and the insight doing so provides into things in general and the limits of ontological inquiry. (shrink)

Being woke, that is, being aware of the appalling injustices borne by many in American society because of certain identities or features and wanting to act to redress these injustices, seems to put one in a quandary: either one can accept a role in the struggle against injustice that seems obviously inefficacious or, if one insists on doing more, one must, it seems, engage in epistemic imperialism, thereby wronging some of those one is endeavoring to help.

One’s involvement with the world seems limited merely to things as they are; hence, modal knowledge—knowledge of what could be or must be simpliciter—should be perplexing. Traditionally, the notion of conceivability has been regarded as crucial to an account of modal knowledge. I believe one has a good deal of such knowledge (though perhaps less than others presume one has). I maintain, however, that conceiving is utterly idle in acquiring modal knowledge: the conceivability of a proposition can provide no evidence (...) whatsoever that what it represents is possible. To show this, I first examine the basis of modal knowledge. I consider what conceivability in general is supposed to be and argue, in light of the preceding considerations, that conceivability is not epistemically efficacious, in the sense of providing evidence, on any proposed specific account. I then maintain that there could be no account of conceivability on which it is epistemically efficacious, that the very idea of the conceivability of a proposition being evidential is misguided. I conclude with some brief recommendations for pursuing a satisfactory modal epistemology. (shrink)

The notion of conceivability has traditionally been regarded as crucial to an account of modal knowledge. Despite its importance to modal epistemology, there is no received explication of conceivability. In recent discussions, some have attempted to explicate the notion in terms of epistemic possibility. There are, however, two notions of epistemic possibility, a more familiar one and a novel one. I argue that these two notions are independent of one another. Both are irrelevant to an account of modal knowledge on (...) the predominant view of modal reality. Only the novel notion is relevant and apt on the competing view of modal reality; but this latter view is problematic in light of compelling counterexamples. Insufficient care regarding the independent notions of epistemic possibility can lead to two problems: a gross problem of conflation and a more subtle problem of obscuring a crucial fact of modal epistemology. Either problem needlessly hampers efforts to develop an adequate account of modal knowledge. I conclude that the familiar notion of epistemic possibility should be eschewed in the context of modal epistemology. (shrink)

Many moral philosophers assume that a person is entitled to respect; this suggests that there is a right to respect. I argue, however, that there is no such right. There can be no right to respect because of what respect is, in conjunction with what a right demands and certain limitations of human agency. In this paper, I first examine the nature and ontological basis of rights. I next consider the notion of respect in general; I adduce several varieties of (...) respect, then present a primary distinction needed to discern the notion of respect relevant to the putative right. Then I propound the argument that there can be no right to respect and consider some means of challenging its conclusion. In closing, I trace some of the consequences of this argument and suggest how it might motivate a different approach to understanding our most basic obligations to one another. (shrink)

This is a book about everything and how anything whatsoever happens. By answering the question what is a thing?, the book reveals what it is to exist, what any being at all is. Such profound matters require a special method of inquiry. The method employed herein – original inquiry – begins with no assumptions about reality. It is, then, a method independent of any figure, trend, or tradition in the history of philosophy. Via this method, one simply confronts all this, (...) the world, an all-encompassing diverse array of whatnot, and on this basis can come to a secure account of what it is to be. In simply confronting the world, however, one’s experience shifts, is transient: all this goes from one way—with, say, a cat here—to some other way—the cat being over there. This manifest inconstancy must be accounted for in any comprehensive account of the world. Yet so must a manifest constancy. If the cat is now, at this moment, over there, that the cat is now, at this moment, over there is forever true. These seemingly contradictory phenomena, inconstancy and constancy, demonstrate the importance of time to understanding the world. Since any legitimate inquiry is directed at something or other and since many objects of inquiry (including inquiry itself) occur over time, correct accounts of temporal reality and of being – of time and the world – provide insight into all inquiry. These accounts provide constraints on and, hence, guidelines for investigating any subject matter in any field. (shrink)

The book_ Fate, Time, and Language: An Essay on Free Will_, published in 2010 by Columbia University Press, presented David Foster Wallace's challenge to Richard Taylor's argument for fatalism. In this anthology, notable philosophers engage directly with that work and assess Wallace's reply to Taylor as well as other aspects of Wallace's thought. With an introduction by Steven M. Cahn and Maureen Eckert, this collection includes essays by William Hasker, Gila Sher, Marcello Oreste Fiocco, Daniel R. Kelly, (...) Nathan Ballantyne, Justin Tosi, and Maureen Eckert. These thinkers explore Wallace's philosophical and literary work, illustrating remarkable ways in which his philosophical views influenced and were influenced by themes developed in his other writings, both fictional and nonfictional. Together with _Fate, Time, and Language_, this critical set unlocks key components of Wallace's work and its traces in modern literature and thought. (shrink)

The genetic code appeared on Earth with the first cells. The codes of cultural evolution arrived almost four billion years later. These are the only codes that are recognized by modern biology. In this book, however, Marcello Barbieri explains that there are many more organic codes in nature, and their appearance not only took place throughout the history of life but marked the major steps of that history. A code establishes a correspondence between two independent 'worlds', and the codemaker (...) is a third party between those 'worlds'. Therefore the cell can be thought of as a trinity of genotype, phenotype and ribotype. The ancestral ribotypes were the agents which gave rise to the first cells. The book goes on to explain how organic codes and organic memories can be used to shed new light on the problems encountered in cell signalling, epigenesis, embryonic development, and the evolution of language. (shrink)

Rapid advancements in human neuroscience and neurotechnology open unprecedented possibilities for accessing, collecting, sharing and manipulating information from the human brain. Such applications raise important challenges to human rights principles that need to be addressed to prevent unintended consequences. This paper assesses the implications of emerging neurotechnology applications in the context of the human rights framework and suggests that existing human rights may not be sufficient to respond to these emerging issues. After analysing the relationship between neuroscience and human rights, (...) we identify four new rights that may become of great relevance in the coming decades: the right to cognitive liberty, the right to mental privacy, the right to mental integrity, and the right to psychological continuity. (shrink)

When subjects view stimulation of a rubber hand while feeling congruent stimulation of their own hand, they may come to feel that the rubber hand is part of their own body. This illusion of body ownership is termed ‘Rubber Hand Illusion’ . We investigated sensitivity of RHI to spatial mismatches between visual and somatic experience. We compared the effects of spatial mismatch between the stimulation of the two hands, and equivalent mismatches between the postures of the two hands. We created (...) the mismatch either by adjusting stimulation or posture of the subject’s hand, or, in a separate group of subjects, by adjusting stimulation or posture of the rubber hand. The matching processes underlying body ownership were asymmetrical. The illusion survived small changes in the subject’s hand posture, but disappeared when the same posture transformations were applied to the rubber hand. Mismatch between the stimulation delivered to the subject’s hand and the rubber hand abolished the illusion. The combination of these two situations is of particular interest. When the subject’s hand posture was slightly different from the rubber hand posture, the RHI remained as long as stimulation of the two hands was congruent in a hand-centred spatial reference frame, even though the altered posture of the subject’s hand meant that stimulation was incongruent in external space. Conversely, the RHI was reduced when the stimulation was incongruent in hand-centred space but congruent in external space. We conclude that the visual–tactile correlation that causes the RHI is computed within a hand-centred frame of reference, which is updated with changes in body posture. Current sensory evidence about what is ‘me’ is interpreted with respect to a prior mental body representation. (shrink)

The increasing availability of brain data within and outside the biomedical field, combined with the application of artificial intelligence (AI) to brain data analysis, poses a challenge for ethics and governance. We identify distinctive ethical implications of brain data acquisition and processing, and outline a multi-level governance framework. This framework is aimed at maximizing the benefits of facilitated brain data collection and further processing for science and medicine whilst minimizing risks and preventing harmful use. The framework consists of four primary (...) areas of regulatory intervention: binding regulation, ethics and soft law, responsible innovation, and human rights. (shrink)

The use of Intelligent Assistive Technology in dementia care opens the prospects of reducing the global burden of dementia and enabling novel opportunities to improve the lives of dementia patients. However, with current adoption rates being reportedly low, the potential of IATs might remain under-expressed as long as the reasons for suboptimal adoption remain unaddressed. Among these, ethical and social considerations are critical. This article reviews the spectrum of IATs for dementia and investigates the prevalence of ethical considerations in the (...) design of current IATs. Our screening shows that a significant portion of current IATs is designed in the absence of explicit ethical considerations. These results suggest that the lack of ethical consideration might be a codeterminant of current structural limitations in the translation of IATs from designing labs to bedside. Based on these data, we call for a coordinated effort to proactively incorporate ethical considerations early in the design and development of new products. (shrink)

Brain–computer interfacing technologies are used as assistive technologies for patients as well as healthy subjects to control devices solely by brain activity. Yet the risks associated with the misuse of these technologies remain largely unexplored. Recent findings have shown that BCIs are potentially vulnerable to cybercriminality. This opens the prospect of “neurocrime”: extending the range of computer-crime to neural devices. This paper explores a type of neurocrime that we call brain-hacking as it aims at the illicit access to and manipulation (...) of neural information and computation. As neural computation underlies cognition, behavior and our self-determination as persons, a careful analysis of the emerging risks of malicious brain-hacking is paramount, and ethical safeguards against these risks should be considered early in design and regulation. This contribution is aimed at raising awareness of the emerging risk of malicious brain-hacking and takes a first step in developing an ethical and legal reflection on those risks. (shrink)

Thomas Sebeok and Noam Chomsky are the acknowledged founding fathers of two research fields which are known respectively as Biosemiotics and Biolinguistics and which have been developed in parallel during the past 50 years. Both fields claim that language has biological roots and must be studied as a natural phenomenon, thus bringing to an end the old divide between nature and culture. In addition to this common goal, there are many other important similarities between them. Their definitions of language, for (...) example, have much in common, despite the use of different terminologies. They both regard language as a faculty, or a modelling system, that appeared rapidly in the history of life and probably evolved as an exaptation from previous animal systems. Both accept that the fundamental characteristic of language is recursion, the ability to generate an unlimited number of structures from a finite set of elements (the property of ‘discrete infinity’). Both accept that human beings are born with a predisposition to acquire language in a few years and without apparent efforts (the innate component of language). In addition to similarities, however, there are also substantial differences between the two fields, and it is an historical fact that Sebeok and Chomsky made no attempt at resolving them. Biosemiotics and Biolinguistics have become two separate disciplines, and yet in the case of language they are studying the same phenomenon, so it should be possible to bring them together. Here it is shown that this is indeed the case. A convergence of the two fields does require a few basic readjustments in each of them, but leads to a unified framework that keeps the best of both disciplines and is in agreement with the experimental evidence. What is particularly important is that such a framework suggests immediately a new approach to the origin of language. More precisely, it suggests that the brain wiring processes that take place in all phases of human ontogenesis (embryonic, foetal, infant and child development) are based on organic codes, and it is the step-by-step appearance of these brain-wiring codes, in a condition that is referred to as cerebra bifida, that holds the key to the origin of language. (shrink)

The existence of different types of semiosis has been recognized, so far, in two ways. It has been pointed out that different semiotic features exist in different taxa and this has led to the distinction between zoosemiosis, phytosemiosis, mycosemiosis, bacterial semiosis and the like. Another type of diversity is due to the existence of different types of signs and has led to the distinction between iconic, indexical and symbolic semiosis. In all these cases, however, semiosis has been defined by the (...) Peirce model, i.e., by the idea that the basic structure is a triad of ‘sign, object and interpretant’, and that interpretation is an essential component of semiosis. This model is undoubtedly applicable to animals, since it was precisely the discovery that animals are capable of interpretation that allowed Thomas Sebeok to conclude that they are also capable of semiosis. Unfortunately, however, it is not clear how far the Peirce model can be extended beyond the animal kingdom, and we already know that we cannot apply it to the cell. The rules of the genetic code have been virtually the same in all living systems and in all environments ever since the origin of life, which clearly shows that they do not depend on interpretation. Luckily, it has been pointed out that semiosis is not necessarily based on interpretation and can be defined exclusively in terms of coding. According to the ‘code model’, a semiotic system is made of signs, meanings and coding rules, all produced by the same codemaker, and in this form it is immediately applicable to the cell. The code model, furthermore, allows us to recognize the existence of many organic codes in living systems, and to divide them into two main types that here are referred to as manufacturing semiosis and signalling semiosis. The genetic code and the splicing codes, for example, take part in processes that actually manufacture biological objects, whereas signal transduction codes and compartment codes organize existing objects into functioning supramolecular structures. The organic codes of single cells appeared in the first three billion years of the history of life and were involved either in manufacturing semiosis or in signalling semiosis. With the origin of animals, however, a third type of semiosis came into being, a type that can be referred to as interpretive semiosis because it became closely involved with interpretation. We realize in this way that the contribution of semiosis to life was far greater than that predicted by the Peirce model, where semiosis is always a means of interpreting the world. Life is essentially about three things: (1) it is about manufacturing objects, (2) it is about organizing objects into functioning systems, and (3) it is about interpreting the world. The idea that these are all semiotic processes, tells us that life depends on semiosis much more deeply and extensively than we thought. We realize in this way that there are three distinct types of semiosis in Nature, and that they gave very different contributions to the origin and the evolution of life. (shrink)

Biosemiotics is the synthesis of biology and semiotics, and its main purpose is to show that semiosis is a fundamental component of life, i.e., that signs and meaning exist in all living systems. This idea started circulating in the 1960s and was proposed independently from enquires taking place at both ends of the Scala Naturae. At the molecular end it was expressed by Howard Pattee’s analysis of the genetic code, whereas at the human end it took the form of Thomas (...) Sebeok’s investigation into the biological roots of culture. Other proposals appeared in the years that followed and gave origin to different theoretical frameworks, or different schools, of biosemiotics. They are: (1) the physical biosemiotics of Howard Pattee and its extension in Darwinian biosemiotics by Howard Pattee and by Terrence Deacon, (2) the zoosemiotics proposed by Thomas Sebeok and its extension in sign biosemiotics developed by Thomas Sebeok and by Jesper Hoffmeyer, (3) the code biosemiotics of Marcello Barbieri and (4) the hermeneutic biosemiotics of Anton Markoš. The differences that exist between the schools are a consequence of their different models of semiosis, but that is only the tip of the iceberg. In reality they go much deeper and concern the very nature of the new discipline. Is biosemiotics only a new way of looking at the known facts of biology or does it predict new facts? Does biosemiotics consist of testable hypotheses? Does it add anything to the history of life and to our understanding of evolution? These are the major issues of the young discipline, and the purpose of the present paper is to illustrate them by describing the origin and the historical development of its main schools. (shrink)

The genetic code appeared on Earth at the origin of life, and the codes of culture arrived almost four billion years later. For a long time it has been assumed that these are the only codes that exist in Nature, and if that were true we would have to conclude that codes are extraordinary exceptions that appeared only at the beginning and at the end of the history of life. In reality, various other organic codes have been discovered in the (...) past few decades and it is likely that more will come to light in the future. The existence of many organic codes in Nature is therefore an experimental fact, but also more than that. It is one of those facts that have extraordinary implications. In this book it is shown that the genetic code was a precondition for the origin of the first cells, the signal transduction codes divided the first cells into three primary kingdoms (Archaea, Bacteria and Eukarya), the splicing codes were instrumental to the origin of the eukaryotic nucleus, the histone code provided a new regulation system in eukaryotic genomes, and the cytoskeleton codes allowed the Eukarya to perform internal movements, including those of mitosis and meiosis. It is shown, furthermore, that organic codes had a key role in multicellular life, in particular in the origin of animals, the origin of mind and the origin of language. The great events of macroevolution, in other words, were associated with the appearance of new organic codes, and we can easily understand why. The reason is that a new code brings into existence something that has never existed before because it creates arbitrary associations, relationships that are not determined by physical necessity. Another outstanding implication is the fact that codes involve meaning and we need therefore to introduce in biology, with the standard methods of science, not only the concept of biological information but also that of biological meaning. The research on biological codes, in conclusion, is bringing to light new mechanisms in evolution and new fundamental concepts in science. This research is the field of Code Biology, the study of all codes of life, from the genetic code to the codes of culture, from the origin of life to the origin of man. (shrink)

Modern biology has not yet come to terms with the presence of many organic codes in Nature, despite the fact that we can prove their existence. As a result, it has not yet accepted the idea that the great events of macroevolution were associated with the origin of new organic codes, despite the fact that this is the most parsimonious and logical explanation of those events. This is probably due to the fact that the existence of organic codes in all (...) fundamental processes of life, and in all major transitions in the history of life, has enormous theoretical implications. It requires nothing less than a new theoretical framework, and that kind of change is inevitably slow. There are too many facts to reconsider, too many bits of history to weave together in a new mosaic. But this is what science is about, and the purpose of the present paper is to show that it can be done. More precisely, it is shown that the whole natural history of the brain can be revisited in the light of the organic codes. What is described here is only a bird’s-eye view of brain macroevolution, but it is hoped that the extraordinary potential of the organic codes can nevertheless come through. The paper contains also another message. The organic codes prove that life is based on semiosis, and are in fact the components of organic semiosis, the first and the most diffused form of semiosis on Earth, but not the only one. It will be shown that the evolution of the brain was accompanied by the development of two new types of sign processes. More precisely, it gave origin first to interpretive semiosis, mostly in vertebrates, and then to cultural semiosis, in our species. (shrink)

Systems Biology and the Modern Synthesis are recent versions of two classical biological paradigms that are known as structuralism and functionalism, or internalism and externalism. According to functionalism (or externalism), living matter is a fundamentally passive entity that owes its organization to external forces (functions that shape organs) or to an external organizing agent (natural selection). Structuralism (or internalism), is the view that living matter is an intrinsically active entity that is capable of organizing itself from within, with purely internal (...) processes that are based on mathematical principles and physical laws. At the molecular level, the basic mechanism of the Modern Synthesis is molecular copying, the process that leads in the short run to heredity and in the long run to natural selection. The basic mechanism of Systems Biology, instead, is self-assembly, the process by which many supramolecular structures are formed by the spontaneous aggregation of their components. In addition to molecular copying and self-assembly, however, molecular biology has uncovered also a third great mechanism at the heart of life. The existence of the genetic code and of many other organic codes in Nature tells us that molecular coding is a biological reality and we need therefore a framework that accounts for it. This framework is Code biology, the study of the codes of life, a new field of research that brings to light an entirely new dimension of the living world and gives us a completely new understanding of the origin and the evolution of life. (shrink)

This book explores how we can measure consciousness. It clarifies what consciousness is, how it can be generated from a physical system, and how it can be measured. It also shows how conscious states can be expressed mathematically and how precise predictions can be made using data from neurophysiological studies.

10. Catholicity Necessary to Sustain Popular Liberty -- 11. Authority and Liberty -- 12. The Works of Daniel Webster -- 13. Schools of Philosophy -- 14. Liberalism and Socialism -- 15. Civil and Religious Freedom -- 16. Liberalism and Progress -- Part III. Freedom and Communion -- 17. The American Republic -- 18. The Democratic Principle -- Notes.